API / Finished Dose Manufacturing Processes and Equipment


Finished Dose - Processes

Dosage Form Introduction

(Back Catalog) Lesson Code: PUF-301. Introduces the concept of dosage forms and the different dosage forms currently in use.

Solid Dosage

(HTML-5 rebuild & remaster in progress - available soon) Lesson Code: PUF-302. Covers solid dose products manufactured by the Pharmaceutical Industry. It describes what ingredients are used and what manufacturing steps are required.

Semisolid Dosage

Lesson Code: PUF-1203. This e-Lesson is aimed at personnel who require an overview of semisolid dosage forms manufactured by the pharmaceutical industry, including their advantages and disadvantages, ingredients used in their manufacture, and the manufacturing steps involved.

Liquid Dosage

(Back Catalog) Lesson Code: PUF-304. Introduces liquid dose products manufactured by the Pharmaceutical Industry. It describes what ingredients are used and what manufacturing steps are required.

Aerosol Inhalers

(HTML-5 rebuild & remaster in progress - available soon) Lesson Code: PUF-305

Water Types & Testing

Lesson Code: PUA-1250. This e-Lesson is targeted towards personnel who require an understanding of the different grades of water typically used in a pharmaceutical manufacturing facility and the tests used to determine water purity.

Water Impurities & Treatment

(Back Catalog) Lesson Code: PUA-551. The most common types of contaminants found and the different treatment steps used to purify water before it can be used in a chemical process.

Process Flow Diagrams (PFDs)

Lesson Code: PUA-1260. Symbols used to represent key process equipment, pipe-work and gauges and how to interpret basic PFDs.

Finished Dose - Equipment

Milling

Lesson Code: PEF-1202. This Lesson provides an overview of milling operations, including different types of milling equipment and techniques, equipment control parameters, and safety precautions.

Blending

Lesson Code: PEF-1203 Blending. This Lesson is aimed at personnel who require an overview of blending operations, including different types of blending equipment, equipment control parameters, and safety precautions.

Filtration for Finished Dose

Lesson Code: PEF-1204. The principle of filtration. Describes the operation of a Plate and Frame Filter Press and outlines equipment control parameters and safety precautions.

Dryers

Lesson Code: PEF-1205. Introduction to drying. The operation of a Tray Drier is described along with drying equipment control parameters and safety precautions.

Fluidized Beds

(HTML-5 rebuild & remaster in progress - available soon) Lesson Code: PEF-306. The process of granulation and the function of a fluidized bed granulator. Also details the equipment’s operation, control parameters, and safety issues.

Tablet Press

Lesson Code: PEF-1207. This Lesson provides an overview of how a tablet press functions, key process control parameters, required in-process checks, and associated safety considerations.

Tablet Coater

(HTML-5 rebuild & remaster in progress - available soon) Lesson Code: PEF-308. The theory of the coating process and the equipment needed. Critical process parameters are also included and explained.

Kettles

(Back Catalog) Lesson Code: PEF-309. The purpose and operation of kettles in finished dose pharmaceutical manufacturing, including control parameters and safety for operators of this type of equipment.

API Manufacturing - Processes

Chemical Reactions – Overview

Lesson Code: PUA-1200. This e-Lesson is aimed at operations personnel in API manufacturing and provides an overview of how chemical reactions are carried out and the various process variables that must be controlled.

Chemical Reactions – Properties

Lesson Code: PUA-1201. This e-Lesson is aimed at operations personnel in API manufacturing and explains the main physical and chemical properties used to monitor and control a chemical reaction.

Distillation & Reflux

Lesson Code: PUA-1210. This e-Lesson is aimed at employees involved in API manufacturing who require an introduction to the principles of distillation and reflux, the critical parameters associated with each process, and the relevant safety precautions that must be taken..

Crystallization

Lesson Code: PUA-1220. This e-Lesson is aimed at employees involved in API manufacturing who require an introduction to the principles of crystallization, the stages and process variables involved in a crystallization process, and the actions that can be taken to resolve some typical process issues.

Drying

Lesson Code: PUA-1230. This e-Lesson is aimed at operations personnel in API manufacturing and it explains the importance of drying products in the API industry, different types of drying equipment, and the control parameters involved in a drying process.

Filtration

Lesson Code: PUA-1240. This e-Lesson is aimed at operations personnel in API manufacturing and provides an overview of the theory of filtration, the types of equipment used, and the key process parameters.

API Manufacturing - Equipment

Chemical Reactor Design

Lesson Code: PEA-1200. How a chemical reactor works and the most important connections needed to carry out a chemical reaction.

Working with Reactors

Lesson Code: PEA-1201. Explains the main tasks involved in operating a chemical reactor such as weighing, charging and taking samples.

Centrifuges

Lesson Code: PEA-1210. This e-Lesson is aimed at operations personnel in API manufacturing and provides an overview of the theory of centrifugation and the operating principles and parameters of Batch Filtering and Inverting Filter Centrifuges.

Reciprocating Pumps

Lesson Code: PEA-1240. This e-Lesson is aimed at personnel who require an overview of reciprocating pumps, their mode of operation, and how they can be used in chemical and pharmaceutical processing.

Rotary & Centrifugal Pumps

Lesson Code: PEA-1241. This e-Lesson is aimed at personnel who require an overview of rotary and centrifugal pumps, their modes of operation, and how they can be used in pharmaceutical processing.

Valves

Lesson Code: PEA-1250. The different types of valves used in a pharmaceutical plant are explained.

Pharma Manufacturing Validation

Fundamentals of Process Validation

Lesson Code: PVF-1130. Introduction to validation in regulated industries using case study of tablet manufacturing process. Includes validation masterplan, validation life cycle, specification, qualification and revalidation.