Lesson Code: PUA-1220. This e-Lesson is aimed at employees involved in API manufacturing who require an introduction to the principles of crystallization, the stages and process variables involved in a crystallization process, and the actions that can be taken to resolve some typical process issues.

  • Category: API Manufacturing - Processes


After taking this e-Lesson, you will be able to:

  • Explain what is meant by the terms 'crystal' and 'crystallization' as they are used in API manufacturing
  • Describe the purpose of a solvent in crystallization and give an example
  • List and explain the key steps in a crystallization process
  • List and explain the process variables that affect the crystallization process
  • Describe the purpose of a 'seed crystal'
  • Describe the purpose and process of recrystallization

KEYWORDS: Agitation, Crystallization, Crystals, Dissolution, Filtration, Impurities, Insoluble, Purification, Recrystallization, Soluble, Solvents, Temperature