Aseptic Processing – Decontamination and Sterilization Technologies

Lesson Code: ASP-1105 (PREMIUM LESSON). This e-Lesson is aimed at personnel in regulated industries who require an overview of methods typically used to decontaminate and sterilize equipment, consumables, containers/closures, and products as part of Aseptic Processing. Methods covered include moist heat, dry heat, hydrogen peroxide vapor, and filtration.

  • Category: Aseptic Processing - Cleanroom GMP

Description

After completing this e-Lesson, you will be able to:

  • Explain why injectable products must be sterile
  • Explain the purpose of cleaning, decontamination, and sterilization in aseptic processing
  • Describe how moist heat sterilization is performed via autoclaving
  • Describe how moist heat sterilization is performed via Steam In Place
  • Describe the purpose of dry heat sterilization and how it is performed
  • Explain the process of HPV decontamination
  • Explain the difference between bioburden filtration and viral filtration
  • Explain what is meant by 'hold times' in relation to equipment used in aseptic processing