Dissolution Testing

(Back Catalog) Lesson Code: PPL-713. How to program the dissolution equipment, carry out media temperature checks, add dosage forms and remove samples. How to calculate dissolution results and when to retest.

  • Category: Analytical Laboratory - Practices


After taking this e-Lesson, you will be able to:

- List the operating parameters that need to be set on the dissolution apparatus

- Describe the final preparation checks that are carried out during a dissolution test

- Explain both methods of dosage form addition: staggering and simultaneous

- Describe the different start time process for staggered and simulataneous dissolutions

- Explain the manual and automatic sampling methods

- Calculate the concentration of active in the vessel, the weight of active dissolved and the percent label claim

- Describe USP acceptance criteria

- List examples of when retesting can be performed